KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCL1
All Species:
26.06
Human Site:
T936
Identified Species:
44.1
UniProt:
Q15111
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15111
NP_006217.3
1095
122728
T936
T
L
S
S
R
L
I
T
S
D
N
T
P
S
V
Chimpanzee
Pan troglodytes
XP_001169560
1095
122728
T936
T
L
S
S
R
L
I
T
S
D
N
T
P
S
V
Rhesus Macaque
Macaca mulatta
XP_001089483
1095
122754
T936
T
L
S
S
R
L
I
T
S
D
N
T
P
S
V
Dog
Lupus familis
XP_536020
1096
122535
T937
T
L
S
S
R
L
I
T
S
D
N
T
P
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3USB7
1096
122654
T937
T
L
S
S
R
L
I
T
S
D
S
T
P
S
V
Rat
Rattus norvegicus
Q62688
1096
122754
T937
T
L
S
S
R
L
I
T
S
D
S
T
P
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507313
1051
118878
G893
A
V
S
S
H
L
V
G
P
D
N
T
S
L
V
Chicken
Gallus gallus
Q2VRL0
637
72514
R516
N
P
L
S
L
S
I
R
L
I
S
G
H
Q
L
Frog
Xenopus laevis
Q32NH8
758
87399
V637
S
A
Q
Q
L
P
K
V
E
N
S
K
E
G
S
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
S663
I
N
T
D
K
P
N
S
I
V
D
P
Q
V
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
I927
K
G
K
S
K
D
D
I
R
N
D
A
N
I
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741067
1068
120024
T895
L
I
H
S
R
M
I
T
L
A
V
N
S
S
P
Sea Urchin
Strong. purpuratus
XP_001178766
684
77475
V563
M
A
N
L
K
Q
C
V
R
S
L
F
N
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
L748
S
T
Q
L
L
P
R
L
N
D
T
S
P
S
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
98.7
96.4
N.A.
94.3
94.1
N.A.
62.9
21.7
24.7
27.9
N.A.
20
N.A.
39
35.8
Protein Similarity:
100
100
99.2
98.5
N.A.
96.6
96.6
N.A.
77.1
34.8
40.4
42.3
N.A.
40.2
N.A.
59.4
48.1
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
46.6
13.3
0
0
N.A.
6.6
N.A.
33.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
60
26.6
20
26.6
N.A.
26.6
N.A.
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
0
0
0
0
0
0
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
8
8
0
0
58
15
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
8
0
0
0
8
0
8
0
% G
% His:
0
0
8
0
8
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
8
0
0
0
0
58
8
8
8
0
0
0
8
0
% I
% Lys:
8
0
8
0
22
0
8
0
0
0
0
8
0
0
8
% K
% Leu:
8
43
8
15
22
50
0
8
15
0
8
0
0
8
15
% L
% Met:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
8
0
0
0
8
0
8
15
36
8
15
0
0
% N
% Pro:
0
8
0
0
0
22
0
0
8
0
0
8
50
0
8
% P
% Gln:
0
0
15
8
0
8
0
0
0
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
50
0
8
8
15
0
0
0
0
8
8
% R
% Ser:
15
0
50
72
0
8
0
8
43
8
29
8
15
50
8
% S
% Thr:
43
8
8
0
0
0
0
50
0
0
8
50
0
8
0
% T
% Val:
0
8
0
0
0
0
8
15
0
8
8
0
0
8
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _